Machine-Learning Algorithms May Accurately Predict Risk for Opioid Overdose

Machine-learning algorithms that incorporate administrative data and deep learning may be effective for predicting risk for opioid overdose and for identifying patients at low risk for overdose, according to a study published in JAMA Network Open. Cancer-free fee-for-service Medicare beneficiaries who filled ≥1 opioid prescription between 2011 and 2015 were included in this prognostic study. The occurrence of fatal or nonfatal opioid overdose, which was defined in 3-month windows following the initial prescription, was identified in each patient. A total of 268 potential predictors (eg, sociodemographics, health status, patterns of opioid use, and practitioner- and regional-level factors) were evaluated for 3-month periods, starting before opioid prescription. The study’s main outcomes included opioid overdose episodes identified with inpatient and emergency department claims. Risk prediction and risk stratification were the primary and secondary goals, respectively, of the analysis. In the study, 3 samples were used (n=186,686 for each): the training sample to develop algorithms, the testing sample to refine algorithms, and the validation sample to evaluate the prediction perfo...

Where Static Electricity Comes From and How It Works

Static electricity is a ubiquitous part of everyday life. It’s all around us, sometimes funny and obvious, as when it makes your hair stand on end, sometimes hidden and useful, as when harnessed by the electronics in your cellphone. The dry winter months are high season for an annoying downside of static electricity – electric discharges like tiny lightning zaps whenever you touch door knobs or warm blankets fresh from the clothes dryer. Static electricity is one of the oldest scientific phenomena people observed and described. Greek philosopher Thales of Miletus made the first account; in his sixth century B.C. writings, he noted that if amber was rubbed hard enough, small dust particles will start sticking to it. Three hundred years later, Theophrastus followed up on Thales’ experiments by rubbing various kinds of stone and also observed the “power of attraction.” But neither of these natural philosophers found a satisfactory explanation for what they saw. It took almost 2,000 more years before the English word “electricity” was first coined, based on the Latin “electricus,” meaning “like amber.” Some of the most famous experiments were conducted by Benjamin Franklin in his qu...

Subway is testing out a meatless meatball sub. Here’s why | Restaurants

Mixed clouds and sun this morning. Scattered thunderstorms developing this afternoon. High 82F. Winds N at 5 to 10 mph. Chance of rain 60%.. Thunderstorms early, then variable clouds overnight with still a chance of showers. Low 66F. Winds ENE at 5 to 10 mph. Chance of rain 80%. The sandwich chain will start selling the product, made with Beyond Meat’s plant-based protein, at 685 restaurants in the United States and Canada next month. The Beyond Meatball Marinara sub will be available for a limited time. Several fast food chains are testing out menu items featuring meat substitutes to attract consumers who want to eat less meat for health or environmental reasons. Dunkin’ recently announced that it is testing out a Beyond Meat sausage in Manhattan. Burger King will start serving a meatless version of its Whopper, featuring a patty made by Beyond competitor Impossible Foods, nationwide this week. White Castle, Carl’s Jr., Tim Hortons, Qdoba and others also have meat substitutes on their menus. For restaurants, testing out the products is a way to cash in on a fast-growing trend. US retail sales of plant-based foods have grown 11% in the past year, according to a...

Genomic inference of the metabolism of cosmopolitan subsurface Archaea, Hadesarchaea

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. The subsurface biosphere is largely unexplored and contains a broad diversity of uncultured microbes1. Despite being one of the few prokaryotic lineages that is cosmopolitan in both the terrestrial and marine subsurface2,​3,​4, the physiological and ecological roles of SAGMEG (South-African Gold Mine Miscellaneous Euryarchaeal Group) Archaea are unknown. Here, we report the metabolic capabilities of this enigmatic group as inferred from genomic reconstructions. Four high-quality (63–90% complete) genomes were obtained from White Oak River estuary and Yellowstone National Park hot spring sediment metagenomes. Phylogenomic analyses place SAGMEG Archaea as a deeply rooting sister clade of the Thermococci, leading us to propose the name Hadesarchaea for this new Archaeal class. With an estimated genome size of around 1.5 Mbp, the genomes of Hadesarchaea a...

Improper heater wiring caused boy’s death while showering, Singapore News & Top Stories

The improper wiring of a water heater to a three-pin plug by workers unlicensed to do electrical work after a Housing Board upgrading programme was behind the death of a 15-year-old boy, who was electrocuted while showering. A coroner’s inquiry into Tan Yao Bin’s death also found that the flat’s circuit breaker, which should have cut off the electrical supply to prevent the tragedy, was faulty as well. The 2016 incident has since led the Housing Board to inform its contractors to alert residents in writing when they find water heaters connected by three-pin plugs. And home owners have also been advised to test their circuit breakers monthly by pushing its test button and seeing if it trips. Yao Bin’s mother, Madam Zhang Aiyan, had decided in 2015 to get a new water heater installed after renovation works at their Bukit Batok flat under the Home Improvement Programme (HIP) were completed. She asked a worker from JL Engineering Construction, the electrical subcontractor for the project, to install the heater. The workman connected the heater to an existing three-pin plug, which was later plugged into a normal wall socket. The worker’s supervisor, Mr ...

(RNS) — Eugene Peterson discovered painfully that the evangelical establishment will immediately seek to destroy anyone

(RNS) — Eugene Peterson discovered painfully that the evangelical establishment will immediately seek to destroy anyone who breaks with their understanding of orthodoxy on LGBTQ issues. The guns were turned on him, posthaste, in a choreography of rejection as public and painful as possible. This has happened so many times before that the real wonder of events last week was that Rev. Peterson somehow did not anticipate that it would happen to him: This is evangelical nuclear deterrence, and it works very well most of the time to beat wonderers and wanderers into submission. But when it fails, and someone strays, those body blows from former evangelical friends are enough to make most anyone shake at the knees. If you do decide to make the break, you have to be spiritually ready. You have to know what’s going to happen. You have to count the cost before saying anything. You have to understand that those who stand with scorned and marginalized people will be scorned and marginalized. You have to realize that whatever abuse you are taking from evangelical authorities is nothing compared to the abuse that LGBTQ people have taken from pastors, teachers, parents, and “Christian friend...

PrintPack 2019: CGSASP to showcase Vpaper Tower for layflat pages

Kunal Gandhi of CGSASP, said, “It is a creasing machine that ensures every single sheet lays open effortlessly. It’s a three-step process: crease, fold and press, press and fold back . Peleman Industries’ innovative technology relaxes the paper fibre through a three-step automated process. The result is a lay-flat book that is easy to read and write on.” CGSASP, at its 70sqm PrintPack stand, will demonstrate the Vpaper Tower machine along with Unifoil table-top digital foiler. These machines were launched at the recently concluded CEIF Photo Fair in New Delhi. Besides this, the CGSASP will highlight Esterlam synthetic plastic doctor blades for coating, label printing, and corrugation applications. CGSASP, which has been representing Tresu’s ancillary business in India, has now extended this partnership with Tresu machinery business, Tresu Solutions. With this, CGSASP will now sell Tresu’s Flexo Innovator high-end package converting machines. “These Flexo Innovator machines are aimed at specialised segments like liquid packaging and mono cartons, paper and pre-print market, sanitary napkins, pouch and lottery printing markets,” informed Gandhi. CGSASP has also joined hands ...

5-Axis CNC Machines Market Research Report, Industry Status, Sales Channels, Market Status, Outlook, Overview and Forecas 2019-2025

Market Research Hub (MRH) has recently uploaded a new study titled Global 5-Axis CNC Machines Market Research Report 2019-2025 to its broad online storehouse. The global 5-Axis CNC Machines market conveniently covers prime factors motivating development and steering industry trends and demand scenarios. Readers can easily quantify market opportunities with the availability of information such as market sizing and market forecasting, thereby being able to analyze the prevailing status across the global 5-Axis CNC Machines market. According to research insights, the worldwide market for 5-Axis CNC Machines accounted a moderately confident growth, with market size estimated to reach million by 2025. Furthermore, the global market is expected to deliver X% CAGR during the slated forecast period. With a purpose to enlighten readers, especially investors and new market entrants, the study centered at 5-Axis CNC Machines market presents an in-depth analysis focusing on recent developments and existing competitive landscape. The striking aspect of this assessment associates to the availability of valuable information related to production capacity and market share, which eventually hel...

Industrial Relay Market Foraying into Emerging Economies FMI Report

A relay is a protecting device used for protection of power systems such as machines, transformers, and generators etc. as it isolates the system from the fault condition in order to prevent damage from electrical overloads such as damage from high rated current and voltages. In order to protect the equipment from high voltages and fault currents relays are used to isolate the equipment from the system. Relay sense the input voltage if it reaches the peak voltage called threshold limit it controls the input voltage if the input voltage exceeds the peak voltage limit it will trigger a signal to circuit breaker. Circuit breaker is a device used to make or break the circuit from the live to protect the complete system from short circuits. Industrial relays are essential to protect the equipment in the system. Several relays operate in industrial applications such as SSR solid state relay, Electro-mechanical relay, overload protection relay, latching relay and other relays. Solid state relay (SSR) switching is completely electronic base where as in electromechanical, operation completely based on opening and closing moving contacts by a magnetic force. Solid state relays are familia...